M.B.B.S-M.B.B.S 1st Year BIOCHEMISTRY - PAPER II(Kerala University of Health Sciences-2014)

Q.P.Code 106001                                                    Reg. No.:…………………

First Professional MBBS Degree Supplementary Examinations,

                                          February 2014
                                  BIOCHEMISTRY - PAPER II

Time : 3 hrs                                                                      Max marks : 50

• Answer all questions

• Draw diagrams wherever necessary

Essay (10)

1. Describe the source, dietary requirements, biochemical functions and deficiency manifestations of vitamin A. (1+1+4+4=10)

 

Short essays (2x5=10)

2. Explain briefly on blood buffers and add a note renal mechanism of maintaining acid base balance. (2+3=5)

3. Describe the process of DNA replication. (5)

 

Short notes (5x3=15)

4. Abnormal hemoglobins

5. Tumor markers

6. Liver function tests

7. Immunoglobulins

8. Gene therapy

 

Answer briefly (5x2=10)

9. Folate antagonists

10. Normal serum concentration of sodium and potassium

11. ELISA ( Enzyme linked immunosorbent assay )

12. What is the normal serum calcium level. Name the hormones regulating serum calcium

13. Enzyme defect in lesch-nyhan syndrome and orotic aciduria

 

Give precise answers (5x1=5)

14. Deficiency of vitamin C

15. Examples for point mutation

16. What are BJP(Bence jones proteins)

17. Name two oncogenes

18. Normal serum uric acid level

***************

Earning:  ₹ 7.25/-