M.Pharm-M.Pharm 2nd Sem Novel Drug Delivery System Part-1 Code: 2920102(Gujarat Technological University-2013)

                    GUJARAT TECHNOLOGICAL UNIVERSITY M. Pharm.

                       SEMESTER – II • EXAMINATION – SUMMER 2013
                    Subject Code: 2920102                  Date: 23-05-2013
                    Subject Name: Novel Drug Delivery System Part-1

Time: 02.30 pm - 05.30 pm                                   Total Marks: 80

 

Instructions:

1. Attempt any five questions. 

2. Make suitable assumptions wherever necessary.

3. Figures to the right indicate full marks.

 

Q.1 (a) Discuss the principle of osmotic drug delivery systems. Classify osmotic drug delivery systems and write a detailed note on controlled porosity osmotic pumps .  06

(b) Write a note on basic components of osmotic drug delivery system giving examples for each component                                         05

(c) Describe Higuchi-Leeper pump                                              05

Q.2 (a) Discuss the rationale for developing colon targeted drug delivery system. Describe in detail about microbially trigerred systems            06

(b) Describe the factors affecting drug absorption from colon targeted drug delivery systems 05

(c) Write a brief note on evaluation of colon targeted drug delivery systems 05

Q.3 (a) Enlist the methods of preparation of liposomes. Write in detail about mechanical dispersion method                                               06

(b) Discuss the evaluation parameters for liposomes                                                             05

(c) Write a short note on application of liposomes in drug targeting                                   05

Q.4 (a) Discuss the strategies employed for taste masking of drugs                                      06

(b) Write a short note on advances in particle coating technology                                       05

(c) Classify pharmaceutical packaging materials with examples                                            05

Q.5 (a) Classify glass containers. Describe the tests for evaluation of suitability of glass as a container 06

(b) Write a note on paper and board based packaging materials                                          05

(c) Write a note on stability aspects of packaging materials                                                   05

Q. 6 (a) Describe the approaches used in developing novel ocular drug delivery systems  06

(b) Write a note on soluble ophthalmic drug insert                                                                05

(c) Discuss the limitations of conventional ocular dosage forms                                           05

Q.7 (a) Discuss about hydrogels as a novel approach to control drug delivery                    06

(b) How are microemulsions evaluated?                                                                                  05

(c) Discuss the advantages and limitations of buccal and sublingual drug delivery             05

Earning:  ₹ 9.00/-