B.Tech-B.Tech Bioinformatics Computational Biology (Sathyabama University, Chennai, Tamil Nadu-2010)
Friday, 23 August 2013 05:58Duraimani
(Established under section 3 of UGC Act,1956)
Course & Branch :B.Tech - BIN
Title of the Paper :Computational Biology Max. Marks :80
Sub. Code :522704/622704 Time : 3 Hours
Date :04/03/2010 Session :AN
PART - A (10 x 2 = 20)
Answer ALL the Questions
1. Define mutant alleles.
2. Differentiate codominance from semidominance.
3. Mention the functional and nonfunctional chromatin.
4. What is karyotyping?
5. Give the structure of nucleotide.
6. Write any two chemical properties of DNA.
7. Mention the 2 simple criteria to distinguish three modes of recombination in bacteria.
8. Write the difference between autonomous replication and integrated replication.
9. List out the three categories of disorders with a genetic basis.
10. What is detected using Pre-natal diagnosis?
PART – B (5 x 12 = 60)
Answer All the Questions
11. Explain Mendelian principle of segregation.
(or)
12. Write in detail about probability in Mendelian inheritance.
13. How can the extent of a chromosome deficiency be determined (a) genetically and (b) cytologically
(or)
14. What is the significance of chromosome inversions and translocations in evolution?
15. Explain any two experiments to prove that the “Transforming principle” is DNA.
(or)
16. (a) List out the chemical bonds important in DNA structures.
(b) Mention any three chemical properties of DNA.
17. What is the basic differences between generalized transduction and specialized transduction? What roles do IS elements play in recombination?
(or)
18. How can genes be mapped by interrupted mating conjugation experiments?
19. Write in detail about gene therapy.
(or)
20. Explain chromosomal abnormalities in detail.
| Earning: ₹ 3.05/- |
