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University of Delhi 2010-2nd Year B.Sc PMCS (Physics, Mathematics, Computer Science) Prog CELL BIOLOGY UNIVERSITY - Question Paper

Monday, 20 May 2013 02:00Web



This question paper contains 4 printed pages]

B.Sc. Prog./II

J


Your Roll No . . .


5180


LS-203: CELL BIOLOGY, BIOCHEMISTRY AND IMMUNOLOGY (NC - Admissions of 2008 and onwards)


Maximum Marks : 75

Time : 3 Hours


(Write your Roll No on the top immediately on receipt of this question paper)

Answer five questions m all, including Q No, 1 which is compulsory

1. (a) Expand the following abbreviations :

(i) NADP (in) PAGE (v) GALT


(ii) GLC (iv) PFK (vi) SCED


3


(b) Differentiate between the following terms :

(i)    Glucogenic amino acid and ketogenic amino acid

(ii)    Oxidative phosphorylation and substrate level of phosphorylation

(lii) Primary immune response and secondary immune response

(iv)    Catalase and Cathepnns

(v)    Glyoxisome and Peroxisome    10

B

RER

Chioroplast Fatty acids PFK NAD

Lysosome    3


Coenzyme Allostenc enzyme Gran urn P-glucosidase Lipase Microsomes


A


(d) Mention the contributions of the following scientists:

(i) Benda

2


(n) E. Knoop

(e) Say True/False

(i) Removal of thymus in neonatal stage will not have any adverse effect (u) Mitochondria is a semiautonomous organell

(hi) Gluconeogenesis occurs in kidney cortex

(iv) Urea cycle takes place partly in

cytoplasm and partly m mitochondria 2

(0 Define the following terms (i) Immunogenecity (n) Turnover number of an enzyme (m) Anaplerouc reaction

(iv)    Deamination

(v)    Amphipathy    5

(g) Mention the location of lymph nodes in human body    2

2    (a) How does C16 Palmitate gets catabolized to

acetyl CoA ?    6

(b) Describe the effect of reversible inhibitors on an enzyme activity Give examples    6

3    Describe the fine structure of Mitochondria and how does it help m ATP synthesis 9    12

4    (a) Draw and label the structure of Golgi

complex.    3

(b)    How does golgi complex enroute primary lysosomes into cclls 9    3

(c)    Describe various polymorphic forms of lysosomes and how peroxisomes differ from lysosomes    6

5    (a) Describe the role of following cells m

immune responses

(l)    B cells

00    Neutrophils

(in)    T cells

(iv)    Dendritic cells

(v)    Eosinophils

(vi)    Natural killer cells    6

(b) Define Allergy How does it develop in an individual 9 Mention some allergic reactions    6

6 (a) What is the role of NADPH+H+, NADH+H+,

and Ribose 5P in ceils ?    3

(b)    How do Ribose 5F and NADPH + H+ are synthesized ?    5

(c)    Describe the process of clonal selection 4

1. Wnte short notes on any three of the following:

(1) Transamination and Deamination,

(n) Ultrastructure of chloroplast (lit) Organ specific autoimmune diseases.

(iv)    Radio isotopes used m Biological systems.

(v)    Gel Electrophoresis.    4,4,4

5180    4    2,000







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