Symbiosis International Education Centre 2007 M.B.A SNAP TEST - Question Paper

“There are 2 steps,” he stated. “The BMP signal to the cells says, ‘Go!’” he stated. “Then info the cells get from the neighborhood where they live tells them to be bone or cartilage. “Over the last 5 or 6 years, dozens of papers have shown that researchers can reliably stimulate natural bone growth in mice, rabbits, dogs and monkeys. Now the 1st tests from human experiments are coming in, and they show success as well, researchers say. 2 small studies in humans were presented at scientific meetings last month by representatives of the Genetic Institute Inc., in Cambridge, Massachusetts. 1 was a study at 4 universities in which twelve dental patients with bone loss in their upper jaws underwent oral surgery in which BMP-2 and a sponge made of artificially produced collagen, a central component of skin and bone, were implanted in the area where was none, and all went on to get implants. The standard treatment for all these cases would have involved surgery of the mouth and also surgery of the harvest bone from the hip for implantation in the mouth. Such procedures are frequently successful, but they are expensive and lengthy and simply cutting down on surgery decreases risk. “We are talking about an outpatient procedure versus the current treatment which involves hospital stay and surgery,” stated Dr. Gerald Riedel, at the bone protein project.

72. What are the major advantages of being able to grow bone over conventional methods like surgery?
1. surgery can be dangerous
2. surgeries are lengthy and expensive, and there is an element of risk involved
3. surgery involves hospital stay
4. all of the above

73. What does Dr Cohen mean when he uses the terms ‘you be bone’ or ‘you be muscle’?
1. the molecules truly tell the cells that they have a option of being either
2. the cells can either become bone or muscle
3. there is a wide variety of tissues in the human body
4. none of the above.

74. What happens once the cells receive the BMP signal?
1. the cells then decide to be bone and muscle
2. the neighboring cells help them take a decision to be bone or cartilage
3. bone or cartilage starts to be formed
4. All of the above
75. A suitable title for the passage would be
1. Bone Boon 2. Bone Technology 3. Bone Time 4. Bone or Bane


76. The main cause why it will be possible to grow bones now is
1. the discovery of the BMP molecule

Earning:   Approval pending.